藥物交互作用
Dienogest / estradiol valerate + Lesinurad
嚴重程度: 中度
Dienogest / estradiol valerate and Lesinurad: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Lesinurad is a weak CYP3A inducer and may lower hormone concentrations in combined oral contraceptives. This could reduce contraceptive efficacy.
用白話說明這項交互作用的意義
Dienogest / estradiol valerate and Lesinurad can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Lesinurad induces CYP3A4, increasing metabolism of estradiol and progestin.
處置方式
Advise an additional non-hormonal contraceptive method during treatment with lesinurad.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Lesinurad 的其他交互作用
常見問題
Can I take Dienogest / estradiol valerate with Lesinurad?
MediHelp rates the interaction as moderate. Dienogest / estradiol valerate and Lesinurad can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lesinurad is a weak CYP3A inducer and may lower hormone concentrations in combined oral contraceptives. This could reduce contraceptive efficacy.
How serious is the interaction between Dienogest / estradiol valerate and Lesinurad?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional non-hormonal contraceptive method during treatment with lesinurad.
What other medicines interact with Lesinurad?
MediHelp also lists interactions of Lesinurad with, for example, Norethisterone, Acetylsalicylic acid, Amiodarone. The full list is on the Lesinurad page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
