藥物交互作用
Ephedrine + Oxytocin
嚴重程度: 嚴重
Ephedrine and Oxytocin: major interaction.
最後更新
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摘要
Oxytocin may cause hypotension, and ephedrine is often used to treat it, but when given after oxytocin a vasopressor can contribute to severe hypertension. This is recognized with oxytocic drugs and vasoconstrictors, particularly in the postpartum period.
用白話說明這項交互作用的意義
Ephedrine and Oxytocin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ephedrine belongs to Cardiovascular; Oxytocin belongs to Endocrine.
為什麼會發生
Additive pressor effects of sympathomimetic vasoconstriction with oxytocic-related vascular effects.
處置方式
Monitor blood pressure frequently and titrate ephedrine in small doses when used with oxytocin. Avoid combining with other vasoconstrictors where possible.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Oxytocin 的其他交互作用
Ephedrine 的其他交互作用
常見問題
Can I take Ephedrine with Oxytocin?
MediHelp rates the interaction as major. Ephedrine and Oxytocin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oxytocin may cause hypotension, and ephedrine is often used to treat it, but when given after oxytocin a vasopressor can contribute to severe hypertension. This is recognized with oxytocic drugs and vasoconstrictors, particularly in the postpartum period.
How serious is the interaction between Ephedrine and Oxytocin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure frequently and titrate ephedrine in small doses when used with oxytocin. Avoid combining with other vasoconstrictors where possible.
What other medicines interact with Oxytocin?
MediHelp also lists interactions of Oxytocin with, for example, Carboprost tromethamine, Dinoprostone, Fexinidazole. The full list is on the Oxytocin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
