藥物交互作用
Oxytocin + Phenylephrine
嚴重程度: 嚴重
Oxytocin and Phenylephrine: major interaction.
最後更新
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摘要
Oxytocin may cause hypotension, while vasopressors given with it can cause severe hypertension. Labeling for oxytocin warns that vasoconstrictors given with it can lead to hypertensive episodes.
用白話說明這項交互作用的意義
Oxytocin and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Oxytocin belongs to Endocrine; Phenylephrine belongs to Respiratory.
為什麼會發生
Additive pharmacodynamic effects; oxytocin-related vascular changes combined with alpha-1 vasoconstriction.
處置方式
Monitor blood pressure closely, for example during obstetric anesthesia, and titrate phenylephrine in small doses.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Phenylephrine 的其他交互作用
Oxytocin 的其他交互作用
常見問題
Can I take Oxytocin with Phenylephrine?
MediHelp rates the interaction as major. Oxytocin and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oxytocin may cause hypotension, while vasopressors given with it can cause severe hypertension. Labeling for oxytocin warns that vasoconstrictors given with it can lead to hypertensive episodes.
How serious is the interaction between Oxytocin and Phenylephrine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely, for example during obstetric anesthesia, and titrate phenylephrine in small doses.
What other medicines interact with Phenylephrine?
MediHelp also lists interactions of Phenylephrine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Phenylephrine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
