藥物交互作用
Ethinyl estradiol-norgestimate + Mineral oil
嚴重程度: 輕微
Ethinyl estradiol-norgestimate and Mineral oil: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Oral mineral oil may dissolve fat-soluble substances in the gut and reduce absorption of lipophilic steroid hormones. In theory this could lower contraceptive hormone exposure, though clinical significance is uncertain with occasional use.
用白話說明這項交互作用的意義
Ethinyl estradiol-norgestimate and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethinyl estradiol-norgestimate belongs to Endocrine; Mineral oil belongs to Gastrointestinal Tract.
為什麼會發生
Mineral oil acts as a lipid solvent in the intestinal lumen, which may reduce absorption of lipophilic drugs.
處置方式
Avoid regular use of mineral oil and take the contraceptive at least 2 hours before or after any dose. Counsel the patient to use backup contraception if prolonged diarrhea or heavy laxative use occurs.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Ethinyl estradiol-norgestimate 的其他交互作用
- Ethinyl estradiol-norgestimate + Fezolinetant 禁忌併用
- Ethinyl estradiol-norgestimate + Ombitasvir / paritaprevir / ritonavir and dasabuvir 禁忌併用
- Ethinyl estradiol-norgestimate + Tranexamic acid 禁忌併用
- Aminocaproic acid + Ethinyl estradiol-norgestimate 嚴重
- Amobarbital + Ethinyl estradiol-norgestimate 嚴重
- Anastrozole + Ethinyl estradiol-norgestimate 嚴重
Mineral oil 的其他交互作用
常見問題
Can I take Ethinyl estradiol-norgestimate with Mineral oil?
MediHelp rates the interaction as minor. Ethinyl estradiol-norgestimate and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral mineral oil may dissolve fat-soluble substances in the gut and reduce absorption of lipophilic steroid hormones. In theory this could lower contraceptive hormone exposure, though clinical significance is uncertain with occasional use.
How serious is the interaction between Ethinyl estradiol-norgestimate and Mineral oil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use of mineral oil and take the contraceptive at least 2 hours before or after any dose. Counsel the patient to use backup contraception if prolonged diarrhea or heavy laxative use occurs.
What other medicines interact with Ethinyl estradiol-norgestimate?
MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-norgestimate page.
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