藥物交互作用
Amisulpride + Vandetanib
嚴重程度: 禁忌併用
Amisulpride and Vandetanib: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Vandetanib has a boxed warning for QT prolongation, torsades de pointes, and sudden death, and its use with other QT-prolonging drugs is to be avoided. Amisulpride would add to this risk.
用白話說明這項交互作用的意義
Amisulpride and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amisulpride belongs to Central Nervous System; Vandetanib belongs to Oncology.
為什麼會發生
Additive QT prolongation through delayed cardiac repolarization.
處置方式
Do not combine; use a non-QT-prolonging alternative to amisulpride. If vandetanib treatment is essential, stop amisulpride.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Amisulpride 的其他交互作用
Vandetanib 的其他交互作用
常見問題
Can I take Amisulpride with Vandetanib?
MediHelp rates the interaction as contraindicated. Amisulpride and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib has a boxed warning for QT prolongation, torsades de pointes, and sudden death, and its use with other QT-prolonging drugs is to be avoided. Amisulpride would add to this risk.
How serious is the interaction between Amisulpride and Vandetanib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use a non-QT-prolonging alternative to amisulpride. If vandetanib treatment is essential, stop amisulpride.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
