藥物交互作用
Gemifloxacin + Vandetanib
嚴重程度: 禁忌併用
Gemifloxacin and Vandetanib: contraindicated interaction.
最後更新
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摘要
Vandetanib has a boxed warning for QT prolongation, torsades de pointes and sudden death. Adding gemifloxacin further increases the arrhythmia risk.
用白話說明這項交互作用的意義
Gemifloxacin and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Gemifloxacin belongs to Anti Bacterial; Vandetanib belongs to Oncology.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Do not combine; use a non-QT-prolonging antibiotic. If a QT-prolonging drug is unavoidable, monitor ECGs and electrolytes frequently.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Gemifloxacin 的其他交互作用
Vandetanib 的其他交互作用
常見問題
Can I take Gemifloxacin with Vandetanib?
MediHelp rates the interaction as contraindicated. Gemifloxacin and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib has a boxed warning for QT prolongation, torsades de pointes and sudden death. Adding gemifloxacin further increases the arrhythmia risk.
How serious is the interaction between Gemifloxacin and Vandetanib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use a non-QT-prolonging antibiotic. If a QT-prolonging drug is unavoidable, monitor ECGs and electrolytes frequently.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
