藥物交互作用
Glipizide-metformin + Niacin
嚴重程度: 中度
Glipizide-metformin and Niacin: moderate interaction.
最後更新
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摘要
Niacin, especially at lipid-lowering doses, can raise blood glucose and worsen glycemic control in diabetes. Antidiabetic doses may need to be increased.
用白話說明這項交互作用的意義
Glipizide-metformin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glipizide-metformin belongs to Endocrine; Niacin belongs to Cardiovascular.
為什麼會發生
Niacin induces insulin resistance and increases hepatic glucose output, opposing antidiabetic drugs.
處置方式
Monitor blood glucose and HbA1c after starting niacin or changing its dose, and adjust glipizide or metformin as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glipizide-metformin 的其他交互作用
Niacin 的其他交互作用
常見問題
Can I take Glipizide-metformin with Niacin?
MediHelp rates the interaction as moderate. Glipizide-metformin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Niacin, especially at lipid-lowering doses, can raise blood glucose and worsen glycemic control in diabetes. Antidiabetic doses may need to be increased.
How serious is the interaction between Glipizide-metformin and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting niacin or changing its dose, and adjust glipizide or metformin as needed.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
