藥物交互作用
Haloperidol + Ibutilide
嚴重程度: 禁忌併用
Haloperidol and Ibutilide: contraindicated interaction.
最後更新
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摘要
Ibutilide causes marked QT prolongation and torsades de pointes, and haloperidol adds to this effect. The combination raises the risk of life-threatening arrhythmia.
用白話說明這項交互作用的意義
Haloperidol and Ibutilide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Haloperidol belongs to Central Nervous System; Ibutilide belongs to Cardiovascular.
為什麼會發生
Additive blockade of repolarizing potassium currents causing QT prolongation.
處置方式
Avoid ibutilide in patients taking haloperidol; consider electrical cardioversion or another antiarrhythmic strategy.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Haloperidol 的其他交互作用
Ibutilide 的其他交互作用
常見問題
Can I take Haloperidol with Ibutilide?
MediHelp rates the interaction as contraindicated. Haloperidol and Ibutilide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ibutilide causes marked QT prolongation and torsades de pointes, and haloperidol adds to this effect. The combination raises the risk of life-threatening arrhythmia.
How serious is the interaction between Haloperidol and Ibutilide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ibutilide in patients taking haloperidol; consider electrical cardioversion or another antiarrhythmic strategy.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Levoketoconazole. The full list is on the Haloperidol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。