藥物交互作用
Haloperidol + Panobinostat
嚴重程度: 禁忌併用
Haloperidol and Panobinostat: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Panobinostat significantly prolongs the QT interval and haloperidol adds to this effect. The combination increases the risk of torsades de pointes and sudden cardiac death.
用白話說明這項交互作用的意義
Haloperidol and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Haloperidol belongs to Central Nervous System; Panobinostat belongs to Oncology.
為什麼會發生
Additive QT interval prolongation via cardiac repolarization effects.
處置方式
Avoid the combination and use an antipsychotic with minimal QT liability. Panobinostat labeling advises against QT-prolonging drugs.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Haloperidol 的其他交互作用
Panobinostat 的其他交互作用
常見問題
Can I take Haloperidol with Panobinostat?
MediHelp rates the interaction as contraindicated. Haloperidol and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Panobinostat significantly prolongs the QT interval and haloperidol adds to this effect. The combination increases the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Haloperidol and Panobinostat?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an antipsychotic with minimal QT liability. Panobinostat labeling advises against QT-prolonging drugs.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
