藥物交互作用
Haloperidol + Sodium phenylbutyrate
嚴重程度: 中度
Haloperidol and Sodium phenylbutyrate: moderate interaction.
最後更新
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摘要
Haloperidol has been reported to raise ammonia in patients with urea cycle disorders, which may undermine phenylbutyrate treatment.
用白話說明這項交互作用的意義
Haloperidol and Sodium phenylbutyrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Haloperidol belongs to Central Nervous System; Sodium phenylbutyrate belongs to Miscellaneous.
為什麼會發生
The mechanism of haloperidol-related hyperammonemia is not well established.
處置方式
Monitor plasma ammonia closely if haloperidol is required. Consider alternatives where possible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Sodium phenylbutyrate 的其他交互作用
Haloperidol 的其他交互作用
常見問題
Can I take Haloperidol with Sodium phenylbutyrate?
MediHelp rates the interaction as moderate. Haloperidol and Sodium phenylbutyrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Haloperidol has been reported to raise ammonia in patients with urea cycle disorders, which may undermine phenylbutyrate treatment.
How serious is the interaction between Haloperidol and Sodium phenylbutyrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor plasma ammonia closely if haloperidol is required. Consider alternatives where possible.
What other medicines interact with Sodium phenylbutyrate?
MediHelp also lists interactions of Sodium phenylbutyrate with, for example, Sodium valproate, Probenecid. The full list is on the Sodium phenylbutyrate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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