藥物交互作用
Insulin aspart + Vitamin b3
嚴重程度: 中度
Insulin aspart and Vitamin b3: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
High-dose niacin, as used for lipid lowering, can impair glucose tolerance and raise blood glucose. This may reduce the glucose-lowering effect of insulin aspart and lead to worsened glycemic control in patients with diabetes.
用白話說明這項交互作用的意義
Insulin aspart and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin aspart belongs to Endocrine; Vitamin b3 belongs to Gastrointestinal Tract.
為什麼會發生
Niacin induces insulin resistance and increases hepatic glucose output, which opposes the glucose-lowering action of insulin.
處置方式
Monitor blood glucose more frequently when starting, adjusting or stopping high-dose niacin. Increase the insulin dose as needed and reduce it again if niacin is withdrawn.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Vitamin b3 的其他交互作用
Insulin aspart 的其他交互作用
常見問題
Can I take Insulin aspart with Vitamin b3?
MediHelp rates the interaction as moderate. Insulin aspart and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose niacin, as used for lipid lowering, can impair glucose tolerance and raise blood glucose. This may reduce the glucose-lowering effect of insulin aspart and lead to worsened glycemic control in patients with diabetes.
How serious is the interaction between Insulin aspart and Vitamin b3?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when starting, adjusting or stopping high-dose niacin. Increase the insulin dose as needed and reduce it again if niacin is withdrawn.
What other medicines interact with Vitamin b3?
MediHelp also lists interactions of Vitamin b3 with, for example, Lovastatin, Simvastatin, Atorvastatin. The full list is on the Vitamin b3 page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。