藥物交互作用
Insulin glulisine + Rosiglitazone
嚴重程度: 嚴重
Insulin glulisine and Rosiglitazone: major interaction.
最後更新
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摘要
Rosiglitazone with insulin raises the risk of hypoglycemia and of edema and congestive heart failure. Combined use is generally discouraged because of the cardiovascular fluid-retention risk.
用白話說明這項交互作用的意義
Insulin glulisine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin glulisine belongs to Endocrine; Rosiglitazone belongs to Endocrine.
為什麼會發生
Rosiglitazone increases insulin sensitivity, adding to insulin effect, and both promote sodium and fluid retention.
處置方式
Avoid in patients with heart failure risk and monitor for edema, rapid weight gain and dyspnea. Reduce insulin if hypoglycemia occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin glulisine 的其他交互作用
Rosiglitazone 的其他交互作用
- Insulin aspart protamine / insulin aspart + Rosiglitazone 嚴重
- Insulin aspart-insulin aspart protamine + Rosiglitazone 嚴重
- Insulin aspart + Rosiglitazone 嚴重
- Insulin degludec / insulin aspart + Rosiglitazone 嚴重
- Insulin degludec-insulin aspart + Rosiglitazone 嚴重
- Insulin degludec-liraglutide + Rosiglitazone 嚴重
常見問題
Can I take Insulin glulisine with Rosiglitazone?
MediHelp rates the interaction as major. Insulin glulisine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin raises the risk of hypoglycemia and of edema and congestive heart failure. Combined use is generally discouraged because of the cardiovascular fluid-retention risk.
How serious is the interaction between Insulin glulisine and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with heart failure risk and monitor for edema, rapid weight gain and dyspnea. Reduce insulin if hypoglycemia occurs.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。