藥物交互作用
Itraconazole + Nizatidine
嚴重程度: 嚴重
Itraconazole and Nizatidine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Itraconazole capsules need gastric acid for absorption, and nizatidine lowers acidity. Reduced itraconazole levels may cause antifungal treatment failure.
用白話說明這項交互作用的意義
Itraconazole and Nizatidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Itraconazole belongs to Anti Fungals; Nizatidine belongs to Gastrointestinal Tract.
為什麼會發生
Reduced acid-dependent dissolution and absorption of itraconazole capsules.
處置方式
Avoid with itraconazole capsules, or use the oral solution or SUBA formulation, which is less dependent on acid. Monitor itraconazole levels and clinical response.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Nizatidine 的其他交互作用
Itraconazole 的其他交互作用
常見問題
Can I take Itraconazole with Nizatidine?
MediHelp rates the interaction as major. Itraconazole and Nizatidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Itraconazole capsules need gastric acid for absorption, and nizatidine lowers acidity. Reduced itraconazole levels may cause antifungal treatment failure.
How serious is the interaction between Itraconazole and Nizatidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with itraconazole capsules, or use the oral solution or SUBA formulation, which is less dependent on acid. Monitor itraconazole levels and clinical response.
What other medicines interact with Nizatidine?
MediHelp also lists interactions of Nizatidine with, for example, Atazanavir, Dasatinib, Erlotinib. The full list is on the Nizatidine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
