藥物交互作用
Levetiracetam + Oliceridine
嚴重程度: 嚴重
Levetiracetam and Oliceridine: major interaction.
最後更新
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摘要
Oliceridine is an opioid and its sedative and respiratory depressant effects may be potentiated by other CNS depressants. Levetiracetam adds to somnolence, so profound sedation is possible.
用白話說明這項交互作用的意義
Levetiracetam and Oliceridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Levetiracetam belongs to Central Nervous System; Oliceridine belongs to Musculoskeletal.
為什麼會發生
Additive central nervous system and respiratory depression (pharmacodynamic).
處置方式
Use the lowest effective oliceridine dose and monitor sedation level and respiratory rate. Reduce the opioid dose if excessive sedation occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Levetiracetam 的其他交互作用
Oliceridine 的其他交互作用
常見問題
Can I take Levetiracetam with Oliceridine?
MediHelp rates the interaction as major. Levetiracetam and Oliceridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oliceridine is an opioid and its sedative and respiratory depressant effects may be potentiated by other CNS depressants. Levetiracetam adds to somnolence, so profound sedation is possible.
How serious is the interaction between Levetiracetam and Oliceridine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective oliceridine dose and monitor sedation level and respiratory rate. Reduce the opioid dose if excessive sedation occurs.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Opium tincture, Sodium oxybate, Sufentanil. The full list is on the Levetiracetam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
