藥物交互作用
Levetiracetam + Sufentanil
嚴重程度: 嚴重
Levetiracetam and Sufentanil: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Sufentanil is a very potent opioid that causes sedation and respiratory depression. Levetiracetam adds to drowsiness, increasing the risk of profound CNS depression.
用白話說明這項交互作用的意義
Levetiracetam and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Levetiracetam belongs to Central Nervous System; Sufentanil belongs to Musculoskeletal.
為什麼會發生
Additive central nervous system and respiratory depression (pharmacodynamic).
處置方式
Use the lowest effective sufentanil dose and monitor sedation and respiratory function continuously in monitored settings.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Levetiracetam 的其他交互作用
Sufentanil 的其他交互作用
常見問題
Can I take Levetiracetam with Sufentanil?
MediHelp rates the interaction as major. Levetiracetam and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Sufentanil is a very potent opioid that causes sedation and respiratory depression. Levetiracetam adds to drowsiness, increasing the risk of profound CNS depression.
How serious is the interaction between Levetiracetam and Sufentanil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective sufentanil dose and monitor sedation and respiratory function continuously in monitored settings.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。