藥物交互作用

Linezolid + Ozanimod

嚴重程度: 禁忌併用

Linezolid and Ozanimod: contraindicated interaction.

最後更新 29 十月 2026 來源: US FDA label

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摘要

Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.

用白話說明這項交互作用的意義

Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Linezolid belongs to Anti Bacterial; Ozanimod belongs to Central Nervous System.

證據等級: Low

為什麼會發生

Additive MAO inhibition and altered ozanimod metabolite exposure.

處置方式

Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.

可向藥師詢問的問題

Is there an alternative to one of these two medicines for me?
If both are essential, who is monitoring me and how often?
Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可解鎖 Linezolid 與 Ozanimod 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

Full clinical management advice
Additional notes
Evidence detail
Interaction checker for a whole prescription

建立免費帳號登入

在網頁版免費試用 Pro+ 7 天，無需信用卡。

參考資料

ZEPOSIA 7-Day Starter Pack - FDA drug label (DailyMed) - section 7 Drug Interactions (names the partner; "and/or its metabolites cannot be ruled out. Prevention or Management: Co-administration of ZEPOSIA with MAO inhibitors (e.g., selegiline, phenelzine, linezolid)") — DailyMed (FDA label)

常見問題

Can I take Linezolid with Ozanimod?

MediHelp rates the interaction as contraindicated. Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.

How serious is the interaction between Linezolid and Ozanimod?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.

What other medicines interact with Linezolid?

MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.

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摘要