藥物交互作用
Oritavancin + Sirolimus
嚴重程度: 輕微
Oritavancin and Sirolimus: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oritavancin is a weak CYP3A4 inducer in vitro and could marginally lower sirolimus concentrations. Since oritavancin is given as a single dose, any effect is likely small and short-lived.
用白話說明這項交互作用的意義
Oritavancin and Sirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oritavancin belongs to Anti Bacterial; Sirolimus belongs to Miscellaneous.
為什麼會發生
Weak CYP3A4 induction by oritavancin may modestly increase sirolimus clearance.
處置方式
No routine dose change is required. Check a sirolimus trough level if there is concern about reduced exposure.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Sirolimus 的其他交互作用
Oritavancin 的其他交互作用
常見問題
Can I take Oritavancin with Sirolimus?
MediHelp rates the interaction as minor. Oritavancin and Sirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer in vitro and could marginally lower sirolimus concentrations. Since oritavancin is given as a single dose, any effect is likely small and short-lived.
How serious is the interaction between Oritavancin and Sirolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is required. Check a sirolimus trough level if there is concern about reduced exposure.
What other medicines interact with Sirolimus?
MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Sirolimus page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
