Drug reference

colesevelam

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Miscellaneous(Hormones))

Mechanism of action

Forms complex with bile acids that is not absorbed through intestine; inhibits enterohepatic reuptake of intestinal bile salts, and this, in turn, increases fecal loss of bile salt-bound LDL and consequently reduces serum cholesterol in patients with primary hypercholesterolemia

Common side effects

  • Upper respiratory tract infection
  • Nasopharyngitis
  • Dyspepsia
  • Constipation
  • Headache
  • Nausea

Related conditions

Frequently asked questions

What drug class is colesevelam?

colesevelam belongs to: Endocrine.

How does colesevelam work?

Forms complex with bile acids that is not absorbed through intestine; inhibits enterohepatic reuptake of intestinal bile salts, and this, in turn, increases fecal loss of bile salt-bound LDL and consequently reduces serum cholesterol in patients with primary hypercholesterolemia

What are the common side effects of colesevelam?

Upper respiratory tract infection, Nasopharyngitis, Dyspepsia, Constipation, Headache, Nausea

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