Drug reference
dupilumab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Respiratory (Monoclonal antibody(Respiratory))
Mechanism of action
Monoclonal antibody that inhibits interleukin-4 (IL-4) and IL-13 signaling by specifically binding to the IL-4R-alpha subunit shared by the IL-4 and IL-13 receptor complexes
Blocking the IL-4R-alpha subunit inhibits IL-4 and IL-13 cytokine-induced responses, including the release of proinflammatory cytokines, chemokines, and IgE
Common side effects
- Arthralgia
- Conjunctivitis
- Injection site reacation
- Keratitis
- Oral herpes
Contraindications
- Known hypersensitivity to dupilumab or its excipients
Related conditions
Frequently asked questions
What drug class is dupilumab?
dupilumab belongs to: Respiratory.
How does dupilumab work?
Monoclonal antibody that inhibits interleukin-4 (IL-4) and IL-13 signaling by specifically binding to the IL-4R-alpha subunit shared by the IL-4 and IL-13 receptor complexes Blocking the IL-4R-alpha subunit inhibits IL-4 and IL-13 cytokine-induced responses, including the release of proinflammatory cytokines, chemokines, and IgE
What are the common side effects of dupilumab?
Arthralgia, Conjunctivitis, Injection site reacation, Keratitis, Oral herpes
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