Drug reference

ocrelizumab

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (MS Drugs)

Mechanism of action

Humanized monoclonal antibody designed to selectively target CD20, a cell surface antigen present on pre-B and mature B lymphocytes, Following cell surface binding to B lymphocytes, ocrelizumab results in antibody-dependent cellular cytolysis and complement-mediated lysis

Common side effects

  • Infusion-related reactions
  • Skin infections
  • Decreased neutrophil counts
  • Lower respiratory tract infections
  • Upper respiratory tract infections

Related conditions

Frequently asked questions

What drug class is ocrelizumab?

ocrelizumab belongs to: Central Nervous System.

How does ocrelizumab work?

Humanized monoclonal antibody designed to selectively target CD20, a cell surface antigen present on pre-B and mature B lymphocytes, Following cell surface binding to B lymphocytes, ocrelizumab results in antibody-dependent cellular cytolysis and complement-mediated lysis

What are the common side effects of ocrelizumab?

Infusion-related reactions, Skin infections, Decreased neutrophil counts, Lower respiratory tract infections, Upper respiratory tract infections

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