Drug interactions
Aminolevulinic acid + Thioridazine
Severity: Moderate
Aminolevulinic acid and Thioridazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thioridazine can cause photosensitivity, and oral aminolevulinic acid causes photosensitization. Using them together may increase the risk of phototoxic skin reactions after exposure to light.
What this interaction means in plain words
Aminolevulinic acid and Thioridazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aminolevulinic acid belongs to Miscellaneous; Thioridazine belongs to Central Nervous System.
Why it happens
Additive phototoxicity from protoporphyrin accumulation and phenothiazine-related photosensitivity.
What to do
Avoid other phototoxic drugs around aminolevulinic acid administration and counsel strict sun and bright-light protection. Reschedule or adjust treatment if thioridazine cannot be withheld.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Other interactions of Aminolevulinic acid
- Acitretin + Aminolevulinic acid Major
- Aminolevulinic acid + Doxycycline Major
- Aminolevulinic acid + Isotretinoin Major
- Aminolevulinic acid + Amiodarone Moderate
- Aminolevulinic acid + Amlodipine-hydrochlorothiazide-valsartan Moderate
- Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide Moderate
Frequently asked questions
Can I take Aminolevulinic acid with Thioridazine?
MediHelp rates the interaction as moderate. Aminolevulinic acid and Thioridazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thioridazine can cause photosensitivity, and oral aminolevulinic acid causes photosensitization. Using them together may increase the risk of phototoxic skin reactions after exposure to light.
How serious is the interaction between Aminolevulinic acid and Thioridazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid other phototoxic drugs around aminolevulinic acid administration and counsel strict sun and bright-light protection. Reschedule or adjust treatment if thioridazine cannot be withheld.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
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