Drug interactions
Amiodarone + Maraviroc
Severity: Minor
Amiodarone and Maraviroc: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amiodarone inhibits P-glycoprotein and could modestly increase maraviroc exposure. Maraviroc has a favorable margin so clinical effect is likely small.
What this interaction means in plain words
Amiodarone and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiodarone belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Amiodarone inhibits P-glycoprotein efflux of maraviroc.
What to do
No routine dose adjustment; monitor for maraviroc adverse effects such as dizziness, hypotension and liver enzyme elevation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Amiodarone with Maraviroc?
MediHelp rates the interaction as minor. Amiodarone and Maraviroc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amiodarone inhibits P-glycoprotein and could modestly increase maraviroc exposure. Maraviroc has a favorable margin so clinical effect is likely small.
How serious is the interaction between Amiodarone and Maraviroc?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose adjustment; monitor for maraviroc adverse effects such as dizziness, hypotension and liver enzyme elevation.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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