Drug interactions
Amlodipine + Verteporfin
Severity: Minor
Amlodipine and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may increase the uptake of verteporfin by vascular endothelial cells and enhance its photodynamic effect. The clinical relevance is uncertain.
What this interaction means in plain words
Amlodipine and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Calcium channel blockers may alter endothelial cell membrane function and increase verteporfin uptake; the mechanism is not firmly established.
What to do
No routine change is needed; follow standard post-treatment light-avoidance precautions and monitor for exaggerated treatment effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Amlodipine with Verteporfin?
MediHelp rates the interaction as minor. Amlodipine and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may increase the uptake of verteporfin by vascular endothelial cells and enhance its photodynamic effect. The clinical relevance is uncertain.
How serious is the interaction between Amlodipine and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; follow standard post-treatment light-avoidance precautions and monitor for exaggerated treatment effects.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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