Drug interactions
Amlodipine-atorvastatin + Eslicarbazepine
Severity: Moderate
Amlodipine-atorvastatin and Eslicarbazepine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eslicarbazepine is a weak CYP3A4 inducer and may reduce concentrations of amlodipine and atorvastatin. The effect can lessen blood pressure and cholesterol control.
What this interaction means in plain words
Amlodipine-atorvastatin and Eslicarbazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-atorvastatin belongs to Cardiovascular; Eslicarbazepine belongs to Central Nervous System.
Why it happens
Eslicarbazepine induces CYP3A4, increasing metabolism of amlodipine and atorvastatin.
What to do
Monitor blood pressure and lipid levels after starting eslicarbazepine, and increase doses of amlodipine or atorvastatin if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-atorvastatin
Other interactions of Eslicarbazepine
- Eslicarbazepine + Mavacamten Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Eslicarbazepine Major
- Avapritinib + Eslicarbazepine Major
- Bedaquiline + Eslicarbazepine Major
- Benzhydrocodone / acetaminophen + Eslicarbazepine Major
Frequently asked questions
Can I take Amlodipine-atorvastatin with Eslicarbazepine?
MediHelp rates the interaction as moderate. Amlodipine-atorvastatin and Eslicarbazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eslicarbazepine is a weak CYP3A4 inducer and may reduce concentrations of amlodipine and atorvastatin. The effect can lessen blood pressure and cholesterol control.
How serious is the interaction between Amlodipine-atorvastatin and Eslicarbazepine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and lipid levels after starting eslicarbazepine, and increase doses of amlodipine or atorvastatin if needed.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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