Drug interactions
Amlodipine-atorvastatin + Etravirine
Severity: Moderate
Amlodipine-atorvastatin and Etravirine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etravirine induces CYP3A4 and can lower concentrations of amlodipine and atorvastatin. Antihypertensive and lipid-lowering effects may be reduced.
What this interaction means in plain words
Amlodipine-atorvastatin and Etravirine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-atorvastatin belongs to Cardiovascular; Etravirine belongs to Anti Virals.
Why it happens
Etravirine induces CYP3A4, increasing metabolism of both components.
What to do
Monitor blood pressure and lipids and titrate doses to effect. Consider a different statin if response is inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-atorvastatin
Other interactions of Etravirine
- Efavirenz + Etravirine Contraindicated
- Etravirine + Isavuconazole Contraindicated
- Amobarbital + Etravirine Major
- Apalutamide + Etravirine Major
- Carbamazepine + Etravirine Major
- Cobicistat + Etravirine Major
Frequently asked questions
Can I take Amlodipine-atorvastatin with Etravirine?
MediHelp rates the interaction as moderate. Amlodipine-atorvastatin and Etravirine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Etravirine induces CYP3A4 and can lower concentrations of amlodipine and atorvastatin. Antihypertensive and lipid-lowering effects may be reduced.
How serious is the interaction between Amlodipine-atorvastatin and Etravirine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and lipids and titrate doses to effect. Consider a different statin if response is inadequate.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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