Drug interactions
Amlodipine-hydrochlorothiazide-valsartan + Maraviroc
Severity: Moderate
Amlodipine-hydrochlorothiazide-valsartan and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension and may add to the effect of antihypertensive drugs. Dizziness and falls are more likely in volume-depleted or older patients.
What this interaction means in plain words
Amlodipine-hydrochlorothiazide-valsartan and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive pharmacodynamic blood-pressure lowering; maraviroc itself is associated with postural hypotension.
What to do
Monitor orthostatic blood pressure when maraviroc is started and counsel on rising slowly. Reduce the antihypertensive dose if symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicated
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Contraindicated
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Contraindicated
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Major
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Major
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Amlodipine-hydrochlorothiazide-valsartan with Maraviroc?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension and may add to the effect of antihypertensive drugs. Dizziness and falls are more likely in volume-depleted or older patients.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor orthostatic blood pressure when maraviroc is started and counsel on rising slowly. Reduce the antihypertensive dose if symptoms occur.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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