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Drug interactions

Ampicillin + Lanthanum carbonate

Severity: Minor

Ampicillin and Lanthanum carbonate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Lanthanum is a polyvalent cation binder that may adsorb oral antibiotics in the gut. Ampicillin binding is not well characterized, but reduced absorption is conceivable and could lower antibiotic exposure.

What this interaction means in plain words

Ampicillin and Lanthanum carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Ampicillin belongs to Anti Bacterial; Lanthanum carbonate belongs to Miscellaneous.

Evidence level: Low

Why it happens

Possible binding of oral ampicillin to lanthanum in the gastrointestinal tract, reducing absorption.

What to do

Give oral ampicillin at least 2 hours before or after lanthanum carbonate.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ampicillin with Lanthanum carbonate?

MediHelp rates the interaction as minor. Ampicillin and Lanthanum carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lanthanum is a polyvalent cation binder that may adsorb oral antibiotics in the gut. Ampicillin binding is not well characterized, but reduced absorption is conceivable and could lower antibiotic exposure.

How serious is the interaction between Ampicillin and Lanthanum carbonate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ampicillin at least 2 hours before or after lanthanum carbonate.

What other medicines interact with Ampicillin?

MediHelp also lists interactions of Ampicillin with, for example, Allopurinol, Bcg vaccine live, Chloramphenicol. The full list is on the Ampicillin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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