Drug interactions
Armodafinil + Nabilone
Severity: Minor
Armodafinil and Nabilone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil promotes wakefulness whereas nabilone is sedating and may cause tachycardia, anxiety and mood changes. The net effect on alertness is unpredictable, and armodafinil may not reliably offset nabilone's impairment of cognition or judgment.
What this interaction means in plain words
Armodafinil and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Nabilone belongs to Gastrointestinal Tract.
Why it happens
Opposing pharmacodynamic effects on arousal; no established pharmacokinetic interaction.
What to do
Do not rely on armodafinil to reverse nabilone sedation or impairment. Monitor heart rate, mood and alertness when the two are used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabilone
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Nabilone?
MediHelp rates the interaction as minor. Armodafinil and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil promotes wakefulness whereas nabilone is sedating and may cause tachycardia, anxiety and mood changes. The net effect on alertness is unpredictable, and armodafinil may not reliably offset nabilone's impairment of cognition or judgment.
How serious is the interaction between Armodafinil and Nabilone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not rely on armodafinil to reverse nabilone sedation or impairment. Monitor heart rate, mood and alertness when the two are used together.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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