Drug interactions
Armodafinil + Saxagliptin
Severity: Minor
Armodafinil and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Saxagliptin is metabolized by CYP3A4 to an active metabolite. Weak induction by armodafinil may slightly alter saxagliptin exposure, with little expected effect on glucose control.
What this interaction means in plain words
Armodafinil and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Saxagliptin belongs to Endocrine.
Why it happens
Weak CYP3A4 induction by armodafinil may increase saxagliptin metabolism.
What to do
No dose adjustment is needed. Monitor glycemic control if armodafinil is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Frequently asked questions
Can I take Armodafinil with Saxagliptin?
MediHelp rates the interaction as minor. Armodafinil and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Saxagliptin is metabolized by CYP3A4 to an active metabolite. Weak induction by armodafinil may slightly alter saxagliptin exposure, with little expected effect on glucose control.
How serious is the interaction between Armodafinil and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor glycemic control if armodafinil is started or stopped.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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