Drug interactions
Azelastine + Hawthorn
Severity: Minor
Azelastine and Hawthorn: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn is an herbal product with reported mild sedative properties, but the evidence for enhancing CNS depression with azelastine is thin. Any effect is likely to be small and based on theory.
What this interaction means in plain words
Azelastine and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelastine belongs to Respiratory; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Possible additive sedation; mechanism not well established.
What to do
Ask patients about herbal use and warn about possible additive drowsiness. No dose change is normally needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azelastine
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Azelastine with Hawthorn?
MediHelp rates the interaction as minor. Azelastine and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn is an herbal product with reported mild sedative properties, but the evidence for enhancing CNS depression with azelastine is thin. Any effect is likely to be small and based on theory.
How serious is the interaction between Azelastine and Hawthorn?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and warn about possible additive drowsiness. No dose change is normally needed.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
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