Drug interactions
Bicalutamide + Levamlodipine
Severity: Minor
Bicalutamide and Levamlodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levamlodipine is metabolized by CYP3A4 and inhibitors can raise exposure, causing hypotension and peripheral edema. Bicalutamide is a weak inhibitor, so the effect is likely small.
What this interaction means in plain words
Bicalutamide and Levamlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bicalutamide belongs to Endocrine; Levamlodipine belongs to Cardiovascular.
Why it happens
Possible weak inhibition of CYP3A4-mediated levamlodipine metabolism by bicalutamide.
What to do
Monitor blood pressure and edema and adjust levamlodipine dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Bicalutamide and Levamlodipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Bicalutamide
- Bicalutamide + Lomitapide Major
- Aminolevulinic acid + Bicalutamide Moderate
- Bicalutamide + Eliglustat Moderate
- Bicalutamide + Flibanserin Moderate
- Bicalutamide + Ivosidenib Moderate
- Bicalutamide + Lonafarnib Moderate
Other interactions of Levamlodipine
- Dantrolene + Levamlodipine Major
- Amiodarone + Levamlodipine Moderate
- Amobarbital + Levamlodipine Moderate
- Apalutamide + Levamlodipine Moderate
- Aprepitant + Levamlodipine Moderate
- Armodafinil + Levamlodipine Moderate
Frequently asked questions
Can I take Bicalutamide with Levamlodipine?
MediHelp rates the interaction as minor. Bicalutamide and Levamlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levamlodipine is metabolized by CYP3A4 and inhibitors can raise exposure, causing hypotension and peripheral edema. Bicalutamide is a weak inhibitor, so the effect is likely small.
How serious is the interaction between Bicalutamide and Levamlodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and edema and adjust levamlodipine dose if needed.
What other medicines interact with Bicalutamide?
MediHelp also lists interactions of Bicalutamide with, for example, Lomitapide, Aminolevulinic acid, Eliglustat. The full list is on the Bicalutamide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
