Drug interactions
Bosutinib + Ivermectin
Severity: Minor
Bosutinib and Ivermectin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bosutinib inhibits P-glycoprotein and may raise ivermectin concentrations. The clinical significance is likely small given ivermectin's wide therapeutic margin.
What this interaction means in plain words
Bosutinib and Ivermectin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bosutinib belongs to Oncology; Ivermectin belongs to Anti Parasitic.
Why it happens
Bosutinib inhibits P-glycoprotein-mediated efflux of ivermectin.
What to do
No dose adjustment is usually needed. Watch for dizziness, neurologic or gastrointestinal adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ivermectin
- Erdafitinib + Ivermectin Moderate
- Ivermectin + Lasmiditan Moderate
- Ivermectin + Quinidine Moderate
- Ivermectin + Rifampin Moderate
- Ivermectin + Sotorasib Moderate
- Ivermectin + Tepotinib Moderate
Other interactions of Bosutinib
- Amiodarone + Bosutinib Major
- Apalutamide + Bosutinib Major
- Aprepitant + Bosutinib Major
- Bosentan + Bosutinib Major
- Bosutinib + Carbamazepine Major
- Bosutinib + Chlorpromazine Major
Frequently asked questions
Can I take Bosutinib with Ivermectin?
MediHelp rates the interaction as minor. Bosutinib and Ivermectin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bosutinib inhibits P-glycoprotein and may raise ivermectin concentrations. The clinical significance is likely small given ivermectin's wide therapeutic margin.
How serious is the interaction between Bosutinib and Ivermectin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Watch for dizziness, neurologic or gastrointestinal adverse effects.
What other medicines interact with Ivermectin?
MediHelp also lists interactions of Ivermectin with, for example, Erdafitinib, Lasmiditan, Quinidine. The full list is on the Ivermectin page.
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