Drug interactions
Bosutinib + Progesterone
Severity: Minor
Bosutinib and Progesterone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Progesterone may inhibit P-glycoprotein, which could modestly raise bosutinib exposure. Clinical significance is uncertain.
What this interaction means in plain words
Bosutinib and Progesterone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bosutinib belongs to Oncology; Progesterone belongs to Endocrine.
Why it happens
Possible P-glycoprotein inhibition by progesterone reducing bosutinib efflux.
What to do
Monitor for bosutinib adverse effects such as diarrhea and liver enzyme elevations. No empirical dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Bosutinib and Progesterone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Progesterone
Other interactions of Bosutinib
- Amiodarone + Bosutinib Major
- Apalutamide + Bosutinib Major
- Aprepitant + Bosutinib Major
- Bosentan + Bosutinib Major
- Bosutinib + Carbamazepine Major
- Bosutinib + Chlorpromazine Major
Frequently asked questions
Can I take Bosutinib with Progesterone?
MediHelp rates the interaction as minor. Bosutinib and Progesterone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Progesterone may inhibit P-glycoprotein, which could modestly raise bosutinib exposure. Clinical significance is uncertain.
How serious is the interaction between Bosutinib and Progesterone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bosutinib adverse effects such as diarrhea and liver enzyme elevations. No empirical dose change is needed.
What other medicines interact with Progesterone?
MediHelp also lists interactions of Progesterone with, for example, Apalutamide, Carbamazepine, Enzalutamide. The full list is on the Progesterone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
