Drug interactions
Bremelanotide + Ergotamine
Severity: Minor
Bremelanotide and Ergotamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bremelanotide may slow gastric emptying and delay absorption of oral drugs such as ergotamine, which could blunt or delay its effect in an acute migraine. The effect is probably small.
What this interaction means in plain words
Bremelanotide and Ergotamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bremelanotide belongs to Genitourinary; Ergotamine belongs to Central Nervous System.
Why it happens
Delayed gastric emptying from bremelanotide may slow oral absorption of ergotamine.
What to do
No routine adjustment is needed; if ergotamine response is delayed, do not repeat doses beyond labeled limits and consider an alternative.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ergotamine
- Almotriptan + Ergotamine Contraindicated
- Atazanavir + Ergotamine Contraindicated
- Clarithromycin + Ergotamine Contraindicated
- Cobicistat + Ergotamine Contraindicated
- Darunavir + Ergotamine Contraindicated
- Dihydroergotamine intranasal + Ergotamine Contraindicated
Other interactions of Bremelanotide
- Bremelanotide + Bupropion-naltrexone Moderate
- Bremelanotide + Cyclosporin Moderate
- Bremelanotide + Digoxin Moderate
- Bremelanotide + Disopyramide Moderate
- Bremelanotide + Naltrexone Moderate
- Bremelanotide + Procainamide Moderate
Frequently asked questions
Can I take Bremelanotide with Ergotamine?
MediHelp rates the interaction as minor. Bremelanotide and Ergotamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bremelanotide may slow gastric emptying and delay absorption of oral drugs such as ergotamine, which could blunt or delay its effect in an acute migraine. The effect is probably small.
How serious is the interaction between Bremelanotide and Ergotamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; if ergotamine response is delayed, do not repeat doses beyond labeled limits and consider an alternative.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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