Drug interactions
Brompheniramine + Lisdexamfetamine
Severity: Minor
Brompheniramine and Lisdexamfetamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating antihistamine, and the stimulant effect of amphetamine may offset its drowsiness. The combination is generally not harmful, but the two effects may mask each other.
What this interaction means in plain words
Brompheniramine and Lisdexamfetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brompheniramine belongs to Respiratory; Lisdexamfetamine belongs to Central Nervous System.
Why it happens
Opposing CNS effects: antihistamine sedation versus amphetamine stimulation.
What to do
No specific action is required. Avoid relying on the stimulant to offset sedation when driving.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lisdexamfetamine
- Isocarboxazid + Lisdexamfetamine Contraindicated
- Linezolid + Lisdexamfetamine Contraindicated
- Lisdexamfetamine + Phenelzine Contraindicated
- Lisdexamfetamine + Procarbazine Contraindicated
- Lisdexamfetamine + Rasagiline Contraindicated
- Lisdexamfetamine + Safinamide Contraindicated
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Lisdexamfetamine?
MediHelp rates the interaction as minor. Brompheniramine and Lisdexamfetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brompheniramine is a sedating antihistamine, and the stimulant effect of amphetamine may offset its drowsiness. The combination is generally not harmful, but the two effects may mask each other.
How serious is the interaction between Brompheniramine and Lisdexamfetamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required. Avoid relying on the stimulant to offset sedation when driving.
What other medicines interact with Lisdexamfetamine?
MediHelp also lists interactions of Lisdexamfetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Lisdexamfetamine page.
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