Drug interactions
Brompheniramine + Metoclopramide
Severity: Minor
Brompheniramine and Metoclopramide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine has anticholinergic and sedative properties that may oppose metoclopramide's prokinetic effect and add to drowsiness. The clinical effect is generally modest.
What this interaction means in plain words
Brompheniramine and Metoclopramide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brompheniramine belongs to Respiratory; Metoclopramide belongs to Gastrointestinal Tract.
Why it happens
Anticholinergic antagonism of prokinetic action and additive sedation.
What to do
Counsel the patient about drowsiness and monitor for reduced symptom relief from metoclopramide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoclopramide
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Metoclopramide?
MediHelp rates the interaction as minor. Brompheniramine and Metoclopramide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brompheniramine has anticholinergic and sedative properties that may oppose metoclopramide's prokinetic effect and add to drowsiness. The clinical effect is generally modest.
How serious is the interaction between Brompheniramine and Metoclopramide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about drowsiness and monitor for reduced symptom relief from metoclopramide.
What other medicines interact with Metoclopramide?
MediHelp also lists interactions of Metoclopramide with, for example, Amantadine, Amoxapine, Antipsychotics (e.g., haloperidol). The full list is on the Metoclopramide page.
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