Drug interactions
Budesonide-formoterol + Posaconazole
Severity: Moderate
Budesonide-formoterol and Posaconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Posaconazole is associated with QT prolongation and formoterol can also prolong QT, especially at higher doses with hypokalemia. Together they may increase the risk of ventricular arrhythmias such as torsades de pointes.
What this interaction means in plain words
Budesonide-formoterol and Posaconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Posaconazole belongs to Anti Fungals.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia adding to the risk.
What to do
Correct potassium and magnesium before and during co-use, and obtain a baseline ECG in patients with cardiac risk factors. Keep formoterol at the lowest effective dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide-formoterol and Posaconazole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide-formoterol
Other interactions of Posaconazole
- Artemether + Posaconazole Contraindicated
- Avanafil + Posaconazole Contraindicated
- Cobimetinib + Posaconazole Contraindicated
- Conivaptan + Posaconazole Contraindicated
- Dihydroergotamine intranasal + Posaconazole Contraindicated
- Dihydroergotamine + Posaconazole Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Posaconazole?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Posaconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Posaconazole is associated with QT prolongation and formoterol can also prolong QT, especially at higher doses with hypokalemia. Together they may increase the risk of ventricular arrhythmias such as torsades de pointes.
How serious is the interaction between Budesonide-formoterol and Posaconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium and magnesium before and during co-use, and obtain a baseline ECG in patients with cardiac risk factors. Keep formoterol at the lowest effective dose.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
