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Drug interactions

Cefditoren + Famotidine

Severity: Moderate

Cefditoren and Famotidine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Famotidine reduces cefditoren absorption, lowering antibiotic exposure. This may compromise treatment of infection.

What this interaction means in plain words

Cefditoren and Famotidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefditoren belongs to Anti Bacterial; Famotidine belongs to Gastrointestinal Tract.

Evidence level: Moderate

Why it happens

Higher gastric pH decreases absorption of cefditoren pivoxil.

What to do

Avoid concurrent H2 blocker use during the course if possible. If it cannot be avoided, monitor for clinical response.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cefditoren with Famotidine?

MediHelp rates the interaction as moderate. Cefditoren and Famotidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Famotidine reduces cefditoren absorption, lowering antibiotic exposure. This may compromise treatment of infection.

How serious is the interaction between Cefditoren and Famotidine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent H2 blocker use during the course if possible. If it cannot be avoided, monitor for clinical response.

What other medicines interact with Famotidine?

MediHelp also lists interactions of Famotidine with, for example, Atazanavir, Dasatinib, Infigratinib. The full list is on the Famotidine page.

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