Drug interactions
Calcium + Chenodiol
Severity: Moderate
Calcium and Chenodiol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids containing calcium may bind chenodiol in the gut and reduce its absorption, lessening gallstone dissolution. The effect on therapeutic outcome is predicted rather than extensively studied.
What this interaction means in plain words
Calcium and Chenodiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Chenodiol belongs to Gastrointestinal Tract.
Why it happens
Adsorption or binding of chenodiol in the gastrointestinal tract, reducing absorption.
What to do
Separate doses by at least 2 hours and monitor response to therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Chenodiol
- Aluminum hydroxide + Chenodiol Moderate
- Calcium carbonate + Chenodiol Moderate
- Chenodiol + Cholestyramine Moderate
- Chenodiol + Colesevelam Moderate
- Chenodiol + Colestipol Moderate
- Chenodiol + Warfarin Moderate
Frequently asked questions
Can I take Calcium with Chenodiol?
MediHelp rates the interaction as moderate. Calcium and Chenodiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antacids containing calcium may bind chenodiol in the gut and reduce its absorption, lessening gallstone dissolution. The effect on therapeutic outcome is predicted rather than extensively studied.
How serious is the interaction between Calcium and Chenodiol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours and monitor response to therapy.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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