Drug interactions
Calcium carbonate + Paromomycin
Severity: Minor
Calcium carbonate and Paromomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral paromomycin is poorly absorbed and acts within the gut lumen, where it may modestly reduce calcium uptake. Clinical consequences are unlikely in most patients.
What this interaction means in plain words
Calcium carbonate and Paromomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Paromomycin belongs to Anti Bacterial.
Why it happens
Paromomycin may alter intestinal mucosal function and bind cations, slightly reducing calcium absorption; this is not well characterized.
What to do
No routine adjustment is needed; check serum calcium if long-term paromomycin is used in a patient reliant on calcium supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Paromomycin
- Cidofovir + Paromomycin Major
- Adefovir + Paromomycin Moderate
- Amikacin + Paromomycin Moderate
- Amphotericin b + Paromomycin Moderate
- Atracurium + Paromomycin Moderate
- Bacitracin-neomycin-polymyxin + Paromomycin Moderate
Frequently asked questions
Can I take Calcium carbonate with Paromomycin?
MediHelp rates the interaction as minor. Calcium carbonate and Paromomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral paromomycin is poorly absorbed and acts within the gut lumen, where it may modestly reduce calcium uptake. Clinical consequences are unlikely in most patients.
How serious is the interaction between Calcium carbonate and Paromomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; check serum calcium if long-term paromomycin is used in a patient reliant on calcium supplements.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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