Drug interactions
Captopril-hydrochlorothiazide + Lanthanum carbonate
Severity: Minor
Captopril-hydrochlorothiazide and Lanthanum carbonate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum can bind to oral drugs in the gut and may reduce absorption of captopril. Reduced absorption could lessen blood pressure control.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Lanthanum carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Captopril-hydrochlorothiazide belongs to Cardiovascular; Lanthanum carbonate belongs to Miscellaneous.
Why it happens
Chelation or binding of the drug by lanthanum cations in the gastrointestinal tract reduces absorption.
What to do
Take captopril at least 2 hours before or after lanthanum carbonate, and monitor blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Captopril-hydrochlorothiazide and Lanthanum carbonate, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Lanthanum carbonate?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Lanthanum carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lanthanum can bind to oral drugs in the gut and may reduce absorption of captopril. Reduced absorption could lessen blood pressure control.
How serious is the interaction between Captopril-hydrochlorothiazide and Lanthanum carbonate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take captopril at least 2 hours before or after lanthanum carbonate, and monitor blood pressure.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
