Drug interactions
Carbamazepine + Finasteride
Severity: Minor
Carbamazepine and Finasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbamazepine is a strong inducer of CYP3A4, which metabolizes finasteride, so finasteride exposure may fall. Reduced efficacy is possible but finasteride has a wide therapeutic margin.
What this interaction means in plain words
Carbamazepine and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbamazepine belongs to Central Nervous System; Finasteride belongs to Genitourinary.
Why it happens
Carbamazepine induces CYP3A4, increasing finasteride clearance.
What to do
No routine dose change is needed. Review clinical response to finasteride (urinary symptoms or hair loss) if carbamazepine is started long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Other interactions of Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contraindicated
- Cabotegravir + Carbamazepine Contraindicated
- Carbamazepine + Delamanid Contraindicated
- Carbamazepine + Dienogest / estradiol valerate Contraindicated
- Carbamazepine + Doravirine Contraindicated
- Carbamazepine + Elbasvir / grazoprevir Contraindicated
Frequently asked questions
Can I take Carbamazepine with Finasteride?
MediHelp rates the interaction as minor. Carbamazepine and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carbamazepine is a strong inducer of CYP3A4, which metabolizes finasteride, so finasteride exposure may fall. Reduced efficacy is possible but finasteride has a wide therapeutic margin.
How serious is the interaction between Carbamazepine and Finasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Review clinical response to finasteride (urinary symptoms or hair loss) if carbamazepine is started long term.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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