Drug interactions
Cefditoren + Nizatidine
Severity: Moderate
Cefditoren and Nizatidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefditoren pivoxil is less well absorbed when gastric acidity is reduced, with lower antibiotic exposure observed with H2 blockers. This may compromise treatment of infection.
What this interaction means in plain words
Cefditoren and Nizatidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefditoren belongs to Anti Bacterial; Nizatidine belongs to Gastrointestinal Tract.
Why it happens
Higher gastric pH decreases absorption of cefditoren pivoxil.
What to do
Avoid concurrent H2 blocker use during the course if possible. If it cannot be avoided, monitor for clinical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nizatidine
- Atazanavir + Nizatidine Major
- Dasatinib + Nizatidine Major
- Erlotinib + Nizatidine Major
- Itraconazole + Nizatidine Major
- Ketoconazole + Nizatidine Major
- Nizatidine + Pazopanib Major
Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
Frequently asked questions
Can I take Cefditoren with Nizatidine?
MediHelp rates the interaction as moderate. Cefditoren and Nizatidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefditoren pivoxil is less well absorbed when gastric acidity is reduced, with lower antibiotic exposure observed with H2 blockers. This may compromise treatment of infection.
How serious is the interaction between Cefditoren and Nizatidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent H2 blocker use during the course if possible. If it cannot be avoided, monitor for clinical response.
What other medicines interact with Nizatidine?
MediHelp also lists interactions of Nizatidine with, for example, Atazanavir, Dasatinib, Erlotinib. The full list is on the Nizatidine page.
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