Drug interactions
Cefditoren + Voclosporin
Severity: Minor
Cefditoren and Voclosporin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin is dose-dependently nephrotoxic, while cefditoren has little intrinsic nephrotoxicity. Additive kidney injury is possible only in susceptible patients and is poorly documented.
What this interaction means in plain words
Cefditoren and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefditoren belongs to Anti Bacterial; Voclosporin belongs to Miscellaneous.
Why it happens
Possible additive renal injury; no established pharmacokinetic interaction.
What to do
Monitor serum creatinine and eGFR as required with voclosporin, and adjust the cefditoren dose in moderate or severe renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Cefditoren with Voclosporin?
MediHelp rates the interaction as minor. Cefditoren and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voclosporin is dose-dependently nephrotoxic, while cefditoren has little intrinsic nephrotoxicity. Additive kidney injury is possible only in susceptible patients and is poorly documented.
How serious is the interaction between Cefditoren and Voclosporin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and eGFR as required with voclosporin, and adjust the cefditoren dose in moderate or severe renal impairment.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
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