Drug interactions
Cefpirome + Sulindac
Severity: Minor
Cefpirome and Sulindac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents are cleared by the kidney, and competition for tubular secretion could modestly raise sulindac exposure. Clinically significant consequences are unlikely.
What this interaction means in plain words
Cefpirome and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefpirome belongs to Anti Bacterial; Sulindac belongs to Musculoskeletal.
Why it happens
Theoretical competition for renal tubular anion secretion.
What to do
No specific action is needed in most patients. Monitor renal function and NSAID adverse effects if kidney function is reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Cefpirome with Sulindac?
MediHelp rates the interaction as minor. Cefpirome and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents are cleared by the kidney, and competition for tubular secretion could modestly raise sulindac exposure. Clinically significant consequences are unlikely.
How serious is the interaction between Cefpirome and Sulindac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed in most patients. Monitor renal function and NSAID adverse effects if kidney function is reduced.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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