Drug interactions
Certolizumab pegol + Human papillomavirus vaccine
Severity: Minor
Certolizumab pegol and Human papillomavirus vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Certolizumab may slightly lessen the immune response to HPV vaccine, although the non-live vaccine is safe to give.
What this interaction means in plain words
Certolizumab pegol and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Certolizumab pegol belongs to Musculoskeletal; Human papillomavirus vaccine belongs to Miscellaneous.
Why it happens
TNF blockade may modestly blunt vaccine-induced immune responses.
What to do
Vaccinate before starting certolizumab where possible; otherwise give the vaccine on schedule.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contraindicated
- Bcg intravesical live + Certolizumab pegol Contraindicated
- Bcg vaccine live + Certolizumab pegol Contraindicated
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine live Contraindicated
Frequently asked questions
Can I take Certolizumab pegol with Human papillomavirus vaccine?
MediHelp rates the interaction as minor. Certolizumab pegol and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Certolizumab may slightly lessen the immune response to HPV vaccine, although the non-live vaccine is safe to give.
How serious is the interaction between Certolizumab pegol and Human papillomavirus vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before starting certolizumab where possible; otherwise give the vaccine on schedule.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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