Drug interactions
Chloral hydrate + Hawthorn
Severity: Minor
Chloral hydrate and Hawthorn: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn is reported to have mild sedative effects and might add to the CNS depression produced by chloral hydrate. Evidence is limited and largely theoretical, and the clinical effect is probably modest.
What this interaction means in plain words
Chloral hydrate and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chloral hydrate belongs to Central Nervous System; Hawthorn belongs to Gastrointestinal Tract.
Why it happens
Possible additive sedative effect; the mechanism of hawthorn's CNS effects is not well established.
What to do
Ask about herbal use and observe for increased drowsiness. Counsel patients to report excessive sedation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chloral hydrate
- Calcium / magnesium / potassium / sodium oxybates + Chloral hydrate Contraindicated
- Chloral hydrate + Sodium oxybate Contraindicated
- Alfentanil + Chloral hydrate Major
- Alprazolam + Chloral hydrate Major
- Amobarbital + Chloral hydrate Major
- Belladonna and opium + Chloral hydrate Major
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Chloral hydrate with Hawthorn?
MediHelp rates the interaction as minor. Chloral hydrate and Hawthorn have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn is reported to have mild sedative effects and might add to the CNS depression produced by chloral hydrate. Evidence is limited and largely theoretical, and the clinical effect is probably modest.
How serious is the interaction between Chloral hydrate and Hawthorn?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use and observe for increased drowsiness. Counsel patients to report excessive sedation.
What other medicines interact with Chloral hydrate?
MediHelp also lists interactions of Chloral hydrate with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Chloral hydrate page.
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