Drug interactions
Chloroquine + Indacaterol-glycopyrronium
Severity: Moderate
Chloroquine and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine prolongs the QTc interval and indacaterol may contribute to QT prolongation and hypokalemia. The combination may increase arrhythmia risk in susceptible patients.
What this interaction means in plain words
Chloroquine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chloroquine belongs to Anti Parasitic; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia.
What to do
Obtain a baseline ECG and check electrolytes, correcting any deficits. Reassess the combination if QTc lengthens significantly or symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Chloroquine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine prolongs the QTc interval and indacaterol may contribute to QT prolongation and hypokalemia. The combination may increase arrhythmia risk in susceptible patients.
How serious is the interaction between Chloroquine and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and check electrolytes, correcting any deficits. Reassess the combination if QTc lengthens significantly or symptoms occur.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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