Drug interactions
Chloroquine + Mirabegron
Severity: Minor
Chloroquine and Mirabegron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine is partly metabolized by CYP2D6 and CYP3A4, so mirabegron could modestly increase exposure. The clinical importance is uncertain, but chloroquine can prolong the QT interval.
What this interaction means in plain words
Chloroquine and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chloroquine belongs to Anti Parasitic; Mirabegron belongs to Genitourinary.
Why it happens
Possible CYP2D6 inhibition by mirabegron; effect not well characterized.
What to do
No routine adjustment is needed. Consider ECG monitoring if other QT-prolonging drugs or risk factors are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirabegron
- Digoxin + Mirabegron Major
- Flecainide + Mirabegron Major
- Mirabegron + Propafenone Major
- Mirabegron + Thioridazine Major
- Amitriptyline + Mirabegron Moderate
- Amoxapine + Mirabegron Moderate
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Mirabegron?
MediHelp rates the interaction as minor. Chloroquine and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloroquine is partly metabolized by CYP2D6 and CYP3A4, so mirabegron could modestly increase exposure. The clinical importance is uncertain, but chloroquine can prolong the QT interval.
How serious is the interaction between Chloroquine and Mirabegron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Consider ECG monitoring if other QT-prolonging drugs or risk factors are present.
What other medicines interact with Mirabegron?
MediHelp also lists interactions of Mirabegron with, for example, Digoxin, Flecainide, Propafenone. The full list is on the Mirabegron page.
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