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Drug interactions

Chlorpromazine + Formoterol-mometasone

Severity: Moderate

Chlorpromazine and Formoterol-mometasone: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Chlorpromazine can prolong the QT interval, and formoterol may increase arrhythmia risk through hypokalemia and tachycardia. Risk is higher at larger doses or with other risk factors.

What this interaction means in plain words

Chlorpromazine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Chlorpromazine belongs to Central Nervous System; Formoterol-mometasone belongs to Respiratory.

Evidence level: Moderate

Why it happens

Additive QT prolongation with beta-2 mediated hypokalemia.

What to do

Check baseline ECG and potassium in at-risk patients and monitor QTc during therapy.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chlorpromazine with Formoterol-mometasone?

MediHelp rates the interaction as moderate. Chlorpromazine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorpromazine can prolong the QT interval, and formoterol may increase arrhythmia risk through hypokalemia and tachycardia. Risk is higher at larger doses or with other risk factors.

How serious is the interaction between Chlorpromazine and Formoterol-mometasone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and potassium in at-risk patients and monitor QTc during therapy.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

Full monographs, dosing and an interaction checker in the MediHelp app

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